I run sa-learn manually with the -ham arg everyday when I know that no SPAM remains that SA missed (not often).
sa-learn --showdots --ham /home/user-data/mail/mailboxes/mymail.tld/user_home_dir/cur/
I only have 1 persistent SPAMMER: Seattle Times but automatically gets put into the Junk folder then I run the perl script to report the SPAMMER to the razor.
perl report_spam.pl /home/user-data/mail/mailboxes/mymail.tld/user_home_dir/.Spam/cur/