Try using Mailgun or Sendgrid for SMTP relay/ Website transactional mails, instead (a FREE 10000 emails/mo or 100 mails/day account are normally enough to cover this kind of needs for all of your WEB server domains).
My friend!.. SMTP relay doesn’t work through MiaB (I don’t know why :/)… My answer is not an advertisement… It’s just the single way you could try to achieve what you asked for.
@pbarney Cool it, please. @just4t is trying to help. Mail-in-a-Box is not normally meant to be a SMTP relay and this forum isn’t for asking for basic system administration help.
To use Mail-in-a-Box as an SMTP relay, you’ll need to configure your server to connect in the same way a mail app would — the documentation for that is in your box’s Mail-in-a-Box control panel. We also have some notes at https://mailinabox.email/advanced-configuration.html.