How to use multiple IPs for sending emails

what do you mean multiple interfaces?

I want to run SENDY, use my ns.box.xyz.com nameservers, and send emails from different domains.

I have 4 IPs with my dedicated server, and can add more, but how to actually use them to spread my outgoing email over?

and how to make sure all are verified senders for all domains (spf/dkim, etc)

thanks!